Laboratory indicators of the composition of peripheral blood in patients with type 1 and type 2 diabetes

Abstract

A comparative analysis of biochemical indicators of carbohydrate metabolism and lipid and lipoprotein composition of blood was carried out in 45 people with type 1 diabetes and 55 people with a diagnosis of type 2 diabetes who were being treated in the endocrinology department.
It was established that in all patients the level of glucose and glycated hemoglobin was significantly increased by an average of 43.3% and 171.4%, respectively. In patients with diabetes mellitus, the concentration of insulin in the blood was significantly higher, and C-peptide was 32% lower than the control values. In patients with type 1 diabetes, there is an increase in cholesterol, triglycerides, LDL, and VLDL. In patients with type 2 diabetes, pronounced changes in the lipid profile of the blood plasma occurred against the background of a decrease in high-density lipoproteins.